Pub. Date : 2013 Jan
PMID : 23353162
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Compared with normal saline and Tween80, propofol and resveratrol at different doses used alone or in combination all significantly alleviated the hepatic pathologies, lowered the apoptosis index (P<0.05), increased Bcl-2 expression (P<0.05), and reduced Bax and caspase-3 expressions in the liver tissues following HIRI (P<0.05). | Resveratrol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 2 | CONCLUSIONS: Propofol and resveratrol can suppress HIRI-induced hepatocyte apoptosis by up-regulating Bcl-2 and down-regulating Bax and caspase-3 expressions, and their combined use can reduce the effective doses of the drugs. | Resveratrol | BCL2 associated X, apoptosis regulator | Rattus norvegicus |