Title : Chemo protective activity of carotenoid meso-zeaxanthin against doxorubicin-induced cardio toxicity.

Pub. Date : 2012

PMID : 23350349






2 Functional Relationships(s)
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1 MZ significantly mitigated DOX-provoked reductions of cardiac activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), as well as depletion of glutathione (GSH).Pretreatment of MZ significantly guarded against DOX-induced rise of oxidative stress markers like lipid peroxidation (LPO), tissue hydroperoxides (HP) and conjugated dienes (CD) in cardiac tissue. Doxorubicin catalase Rattus norvegicus
2 MZ significantly mitigated DOX-provoked reductions of cardiac activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), as well as depletion of glutathione (GSH).Pretreatment of MZ significantly guarded against DOX-induced rise of oxidative stress markers like lipid peroxidation (LPO), tissue hydroperoxides (HP) and conjugated dienes (CD) in cardiac tissue. Doxorubicin catalase Rattus norvegicus