Title : Galectin-3 deficiency accelerates high-fat diet-induced obesity and amplifies inflammation in adipose tissue and pancreatic islets.

Pub. Date : 2013 Jun

PMID : 23349493






1 Functional Relationships(s)
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1 In vitro stimulation of LGALS3(-/-) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1-dependent IL-1beta production and increased phosphorylation of NF-kappaB p65 compared with WT cells. saturated fatty acid palmitate caspase 1 Mus musculus