Title : Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

Pub. Date : 2013 Mar 15

PMID : 23340295






1 Functional Relationships(s)
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1 CONCLUSIONS: These findings signify a unique role for OATP1B1 and OATP1B3 in the elimination of sorafenib-glucuronide and suggest a role for these transporters in the in vivo handling of glucuronic acid conjugates of drugs. Glucuronides solute carrier organic anion transporter family member 1B3 Homo sapiens