Title : Association between polymorphisms of XRCC1 Arg399Gln and XPD Lys751Gln genes and prognosis of colorectal cancer in a Chinese population.

Pub. Date : 2012

PMID : 23317245






2 Functional Relationships(s)
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1 We conducted this study to detect associations between XRCC1 Arg399Gln and XPD Lys751Gln genotypes and survival of colorectal cancer patients treated with 5-FU/oxalipatin chemotherapy. Fluorouracil X-ray repair cross complementing 1 Homo sapiens
2 In conclusion, it is suggested that the XRCC1 Arg399Gln and XPD Lys751Gln polymorphisms should be routinely assessed to determine colorectal patients who are more likely to benefit from 5-FU/oxalipatin chemotherapy. Fluorouracil X-ray repair cross complementing 1 Homo sapiens