Pub. Date : 2013 Mar
PMID : 23313706
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An 8-week co-administration of both D-gal (300 mg/kg s.c.) and huperzine A (0.1 mg/kg s.c.) not only significantly decreased hepatic function impairment, ROS generation, oxidative damage, but also suppressed inflamm-aging by inhibiting hepatic replicative senescence, AChE activity, IkappaBalpha degradation, NF-kappaB p65 nuclear translocation and inflammatory responses. | huperzine A | acetylcholinesterase | Rattus norvegicus |
| 2 | Huperzine A exhibited protective effects against D-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. | huperzine A | acetylcholinesterase | Rattus norvegicus |