Title : Prolonged diet induced obesity has minimal effects towards brain pathology in mouse model of cerebral amyloid angiopathy: implications for studying obesity-brain interactions in mice.

Pub. Date : 2013 Sep

PMID : 23313575






2 Functional Relationships(s)
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1 Taken together, these data show that prolonged DIO has only modest effects towards Abeta in a mouse model of CAA, but appears to elevate some localized microglial reactivity within the hippocampal gyri and selective markers of inflammatory signaling. 3,3'-Dioctadecyloxacarbocyanine perchlorate amyloid beta (A4) precursor protein Mus musculus
2 These data are consistent with the majority of the existing literature in other models of Abeta pathology, which surprisingly show a mixed profile of DIO effects towards pathological processes in mouse models of neurodegenerative disease. 3,3'-Dioctadecyloxacarbocyanine perchlorate amyloid beta (A4) precursor protein Mus musculus