Pub. Date : 2013 Mar-Apr
PMID : 23295110
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TNF-induced nuclear translocation of NF-kappaB was abolished by treatment with CZP. | Certolizumab Pegol | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | CONCLUSIONS: We have found at cellular level, that a clinically available TNF inhibitor, CZP i) reduces adhesion molecule expression; ii) prevents TNF-induced activation of the NF-kappaB pathway and iii) prevents the production of microparticles by activated endothelial cells. | Certolizumab Pegol | nuclear factor kappa B subunit 1 | Homo sapiens |