Title : Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex.

Pub. Date : 2013 Feb 22

PMID : 23293029






1 Functional Relationships(s)
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1 The data further indicate that eIF1 dissociation must be accompanied by the movement of the eIF1A CTT toward eIF5 in order to trigger release of phosphate from eIF2, which converts the latter to its GDP-bound state. Guanosine Diphosphate eukaryotic translation initiation factor 5 Homo sapiens