Protein Name eukaryotic translation initiation factor 5
Organism Homo sapiens
Gene ID 1983
Gene Symbol

EIF5

UniProt P55010 (IF5_HUMAN), A0A024R6Q1 (A0A024R6Q1_HUMAN)
Relationships Total Number of functionally related compound(s) : 22
Total Number of Articles : 41
Description

eukaryotic translation initiation factor 5

Gene Summary

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

synonyms
  • eukaryotic translation initiation factor 5
  • EIF-5
  • EIF-5A
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Properties