Pub. Date : 2013 Mar
PMID : 23291720
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Rotenone increased phosphorylation of c-Jun NH2-terminal kinase (JNK) and p38 MAPK, whereas nicardipine blocked these increases. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Rotenone increased phosphorylation of c-Jun NH2-terminal kinase (JNK) and p38 MAPK, whereas nicardipine blocked these increases. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
3 | These results indicate that nicardipine exerts a protective effect against rotenone-induced apoptosis in SH-SY5Y cells, inhibiting phosphorylation of JNK and p38 MAPK and activation of CASPs. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |