Title : The effect of phytic acid on the expression of NF-kappaB, IL-6 and IL-8 in IL-1beta-stimulated human colonic epithelial cells.

Pub. Date : 2012 Nov-Dec

PMID : 23285696






4 Functional Relationships(s)
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Protein Name
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1 The effect of phytic acid on the expression of NF-kappaB, IL-6 and IL-8 in IL-1beta-stimulated human colonic epithelial cells. Phytic Acid nuclear factor kappa B subunit 1 Homo sapiens
2 IP6 at all used concentrations had no influence on transcription of p65 gene and modulated expression of p50 and IkappaBalpha genes in Caco-2 cells. Phytic Acid nuclear factor kappa B subunit 1 Homo sapiens
3 The results of these studies suggest that IP6 may exert immunoregulatory effects on intestinal epithelium by influencing transcriptional activity of genes encoding p50 subunit of NF-kappaB, its inhibitor IkappaBalpha and proinflammatory cytokines IL-6 and IL-8. Phytic Acid nuclear factor kappa B subunit 1 Homo sapiens
4 The results of these studies suggest that IP6 may exert immunoregulatory effects on intestinal epithelium by influencing transcriptional activity of genes encoding p50 subunit of NF-kappaB, its inhibitor IkappaBalpha and proinflammatory cytokines IL-6 and IL-8. Phytic Acid nuclear factor kappa B subunit 1 Homo sapiens