Pub. Date : 2013 Feb
PMID : 23275307
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment of animals with acetaminophen elevated ALT and nitrite/nitrate concentration in the plasma, enhanced iNOS and NF-kappaB expression and reduced GSH and cAMP concentration in the liver. | Acetaminophen | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Our investigation indicates that glucagon has a moderately protective effect against acetaminophen-induced liver injury, which is, at least partially, mediated through the downregulation of iNOS and through the increase in hepatic cAMP content, but it is not mediated through the modulation of NF-kappaB activity. | Acetaminophen | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |