Title : Mechanisms of MPP⁺-induced PC12 cell apoptosis via reactive oxygen species.

Pub. Date : 2012 Dec

PMID : 23271287






2 Functional Relationships(s)
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1 The elevated ROS was strongly associated with the activation of JNK and ERK1/2 signal pathways after MPP(+) exposure, since the pretreatment of NAC significantly reduced the upregulation of p-JNK and p-ERK1/2. Acetylcysteine mitogen-activated protein kinase 8 Rattus norvegicus
2 The elevated ROS was strongly associated with the activation of JNK and ERK1/2 signal pathways after MPP(+) exposure, since the pretreatment of NAC significantly reduced the upregulation of p-JNK and p-ERK1/2. Acetylcysteine mitogen-activated protein kinase 8 Rattus norvegicus