Pub. Date : 2013 Feb 8
PMID : 23264626
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 2 | Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 3 | We also examined how these interrelationships changed with an intervention by feeding mice either a control diet or one containing the brain permeable beta-amyloid and Tau aggregate binding molecule curcumin. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 4 | Curcumin selectively suppressed levels of soluble Tau dimers, but not of insoluble and monomeric phospho-Tau, while correcting behavioral, synaptic, and HSP deficits. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 5 | In summary, curcumin reduced soluble Tau and elevated HSPs involved in Tau clearance, showing that even after tangles have formed, Tau-dependent behavioral and synaptic deficits can be corrected. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 6 | In summary, curcumin reduced soluble Tau and elevated HSPs involved in Tau clearance, showing that even after tangles have formed, Tau-dependent behavioral and synaptic deficits can be corrected. | Curcumin | microtubule associated protein tau | Homo sapiens |
| 7 | In summary, curcumin reduced soluble Tau and elevated HSPs involved in Tau clearance, showing that even after tangles have formed, Tau-dependent behavioral and synaptic deficits can be corrected. | Curcumin | microtubule associated protein tau | Homo sapiens |