Title : [Mechanism of apoptosis synergistically induced by bortezomib combined with cytarabine in U937 cell line].

Pub. Date : 2012 Dec

PMID : 23257432






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 It is concluded that the apoptosis of U937 cells synergistically induced by bortezomib combined with low concentration Ara-C is possibly associated with up-regulation of phosphorylated form of JNK, P38 and down-regulation of phosphorylation of ERK induced by increase of ROS, resulting in decrease of mitochondrial potential. Bortezomib mitogen-activated protein kinase 8 Homo sapiens