Title : Age-modulated association between prefrontal NAA and the BDNF gene.

Pub. Date : 2013 Jul

PMID : 23253771






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Age-modulated association between prefrontal NAA and the BDNF gene. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
2 However, few studies have explored the relationship between BDNF polymorphisms and NAA levels directly. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
3 Here, we present data from a single-voxel proton magnetic resonance spectroscopy study of 64 individuals and explore the relationship between BDNF polymorphisms and prefrontal NAA level. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
4 Our results indicate an association between a single nucleotide polymorphism (SNP) within BDNF, known as rs1519480, and reduced NAA level (p = 0.023). N-acetylaspartate brain derived neurotrophic factor Homo sapiens
5 The rs1519480 SNP influences BDNF mRNA expression and has an impact on prefrontal NAA level over time. N-acetylaspartate brain derived neurotrophic factor Homo sapiens