Pub. Date : 2013 Mar
PMID : 23249147
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Protective effect of quercetin on lead-induced oxidative stress and endoplasmic reticulum stress in rat liver via the IRE1/JNK and PI3K/Akt pathway. | Quercetin | AKT serine/threonine kinase 1 | Rattus norvegicus |
2 | Additionally, quercetin dramatically increased Phosphoinositide-3-kinase (PI3K) and phosphorylated protein kinase B (PKB/Akt) levels in liver rats. | Quercetin | AKT serine/threonine kinase 1 | Rattus norvegicus |
3 | Taken together, these results suggested that the inhibition of Pb-induced ER stress by quercetin is due at least in part to its anti-oxidant stress activity and its ability to modulate the PI3K/Akt and IRE1/JNK signaling pathway. | Quercetin | AKT serine/threonine kinase 1 | Rattus norvegicus |