Title : Free enthalpies of replacing water molecules in protein binding pockets.

Pub. Date : 2012 Dec

PMID : 23247390






1 Functional Relationships(s)
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1 In this study, we investigate the displacement of water molecules by an apolar probe in the binding pocket of two proteins, cyclin-dependent kinase 2 and tRNA-guanine transglycosylase, using the method of enveloping distribution sampling (EDS) to obtain free enthalpy differences. Water queuine tRNA-ribosyltransferase catalytic subunit 1 Homo sapiens