Protein Name queuine tRNA-ribosyltransferase catalytic subunit 1
Organism Homo sapiens
Gene ID 81890
Gene Symbol

QTRT1

UniProt Q9BXR0 (TGT_HUMAN), Q71RF8 (Q71RF8_HUMAN)
Relationships Total Number of functionally related compound(s) : 111
Total Number of Articles : 122
Description

queuine tRNA-ribosyltransferase catalytic subunit 1

Gene Summary

This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]

synonyms
  • queuine tRNA-ribosyltransferase catalytic subunit 1
  • TGT, 43-KD subunit
  • TGT, catalytic subunit
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Properties