Title : Effect of long-term piceatannol treatment on eNOS levels in cultured endothelial cells.

Pub. Date : 2013 Jan 18

PMID : 23246837






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1 Effect of long-term piceatannol treatment on eNOS levels in cultured endothelial cells. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
2 It was suggested that endothelial NO synthase (eNOS) might be involved in piceatannol-induced acute vasorelaxation. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
3 It was suggested that endothelial NO synthase (eNOS) might be involved in piceatannol-induced acute vasorelaxation. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
4 Here, we investigated the expression of eNOS in EA.hy926 human umbilical vein cells after long-term treatment with piceatannol, and compared this effect with that of resveratrol, an analog of piceatannol. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
5 Long-term treatment with piceatannol up-regulated eNOS mRNA expression and increased eNOS protein expression in a dose-dependent manner. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
6 Long-term treatment with piceatannol up-regulated eNOS mRNA expression and increased eNOS protein expression in a dose-dependent manner. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
7 Moreover, piceatannol increased the levels of phosphorylated eNOS. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens
8 These findings indicate that piceatannol may improve vascular function by up-regulating eNOS expression. 3,3',4,5'-tetrahydroxystilbene nitric oxide synthase 3 Homo sapiens