Title : Risk factors for sorafenib-induced high-grade skin rash in Japanese patients with advanced renal cell carcinoma.

Pub. Date : 2013 Mar

PMID : 23237922






1 Functional Relationships(s)
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1 Of these, 33 patients were subjected to HLA typing and polymorphism analyses of CYP3A5, ABCB1, ABCC2, and UGT1A1, which are involved in the metabolism and membrane transport of sorafenib. Sorafenib cytochrome P450 family 3 subfamily A member 5 Homo sapiens