Title : A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity.

Pub. Date : 2013 Feb

PMID : 23230267






1 Functional Relationships(s)
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1 Cellular ceramide and S1P levels rose in parallel with CAMP levels following addition of either exogenous cell-permeating ceramide (C2Cer), which increases S1P production, or thapsigargin (an ER stressor), applied to cultured human skin keratinocytes or topically to mouse skin. Thapsigargin sphingosine-1-phosphate receptor 1 Mus musculus