Title : Carmustine enhances the anticancer activity of selenite in androgen-independent prostate cancer cells.

Pub. Date : 2012

PMID : 23204869






1 Functional Relationships(s)
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1 Treatment of PC-3 cells with a combination of nontoxic selenite and carmustine resulted in greater increases in cytotoxicity, reactive oxygen species generation, growth inhibition, apoptosis, and DNA double-strand breaks, with concomitant decreases in DNA synthesis, glutathione, glutathione reductase, and antiapoptotic proteins. Carmustine glutathione-disulfide reductase Homo sapiens