Pub. Date : 2013 Feb
PMID : 23183129
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition, NAC-treated rats showed upregulated expression of NKCC2, AQP2, and UT-A1; elevated Klotho protein expression, low p53 expression, and few ED-1 positive cells. | Acetylcysteine | aquaporin 2 | Rattus norvegicus |
2 | In conclusion, we attribute these beneficial effects of NAC (the significant improvements in inulin clearance and in the expression of NKCC2, AQP2, and UT-A1) to its ability to decrease oxidative stress, inhibit p53 expression, minimize kidney inflammation, and stimulate Klotho expression. | Acetylcysteine | aquaporin 2 | Rattus norvegicus |