Title : Differential effect of zoledronic acid on human vascular smooth muscle cells.

Pub. Date : 2013 Jun 15

PMID : 23164362






1 Functional Relationships(s)
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1 CONCLUSIONS: These data suggest that ZA is effective in inhibiting HASMC proliferation, adhesion, and migration, which coincide with the appearance of unprenylated RAP-1A/B protein, thereby suggesting that the mevalonate pathway may play a role in the inhibition of HASMC activation. Mevalonic Acid RAP1A, member of RAS oncogene family Homo sapiens