Title : Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.

Pub. Date : 2012 Nov 1

PMID : 23132899






1 Functional Relationships(s)
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1 RESULTS: We found that STC induces apoptosis in these cells in a dose-dependent manner and leads to the activation of Fas and caspase-8, cleavage of Bid, mitochondrial damage, and activation of caspase-3. stichoposide BH3 interacting domain death agonist Homo sapiens