Title : Major T cell response to a mycolyl glycolipid is mediated by CD1c molecules in rhesus macaques.

Pub. Date : 2013 Jan

PMID : 23132493






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Human CD1b molecules contain a maze of hydrophobic pockets and a tunnel capable of accommodating the unusually long, branched acyl chain of mycolic acids, an essential fatty acid component of the cell wall of mycobacteria. Mycolic Acids CD1b molecule Homo sapiens
2 It has been accepted that CD1b-bound mycolic acids constitute a scaffold for mycolate-containing (glyco)lipids stimulating CD1b-restricted T cells. Mycolic Acids CD1b molecule Homo sapiens
3 It has been accepted that CD1b-bound mycolic acids constitute a scaffold for mycolate-containing (glyco)lipids stimulating CD1b-restricted T cells. Mycolic Acids CD1b molecule Homo sapiens
4 Remarkable homology in amino acid sequence is observed between human and monkey CD1b molecules, and indeed, monkey CD1b molecules are able to bind glucose monomycolate (GMM), a glucosylated species of mycolic acids, and present it to specific human T cells in vitro. Mycolic Acids CD1b molecule Homo sapiens
5 Remarkable homology in amino acid sequence is observed between human and monkey CD1b molecules, and indeed, monkey CD1b molecules are able to bind glucose monomycolate (GMM), a glucosylated species of mycolic acids, and present it to specific human T cells in vitro. Mycolic Acids CD1b molecule Homo sapiens