Title : Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.

Pub. Date : 1990 Jan

PMID : 2313206






1 Functional Relationships(s)
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1 When a bolus dose of mevinolinic acid was coupled with a continuous infusion of mevalonate, the product of the reaction catalyzed by HMG-CoA reductase, the mevinolinic acid-induced decrease in cholesterol 7 alpha-hydroxylase activity and bile acid synthesis was prevented. Mevalonic Acid 3-hydroxy-3-methylglutaryl-CoA reductase Rattus norvegicus