Title : Live-cell imaging of endogenous Ras-GTP shows predominant Ras activation at the plasma membrane and in the nucleus in Saccharomyces cerevisiae.

Pub. Date : 2013 Feb

PMID : 23127800






1 Functional Relationships(s)
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1 Remarkably, in a gpa2Delta, but not in a gpr1Delta mutant, active Ras accumulates in internal membranes and mitochondria, both when cells are growing on glucose medium or are starved, indicating that Gpa2, but not Gpr1 is required for the recruitment of Ras-GTP at the plasma membrane and in the nucleus. Radium Gpr1p Saccharomyces cerevisiae S288C