Title : Etoposide sensitizes neuroblastoma cells expressing caspase 8 to TRAIL.

Pub. Date : 2012 Jun 21

PMID : 23124518






2 Functional Relationships(s)
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1 In addition, sequential treatment with etoposide and TRAIL increased caspases 8, 9 and 3 activation, Mcl-1 cleavage and Bid truncation, which suggests that the ability of etoposide and TRAIL to induce apoptosis is mediated through activation of an intrinsic signalling pathway. Etoposide MCL1 apoptosis regulator, BCL2 family member Homo sapiens
2 In addition, sequential treatment with etoposide and TRAIL increased caspases 8, 9 and 3 activation, Mcl-1 cleavage and Bid truncation, which suggests that the ability of etoposide and TRAIL to induce apoptosis is mediated through activation of an intrinsic signalling pathway. Etoposide MCL1 apoptosis regulator, BCL2 family member Homo sapiens