Title : Monoacylglycerol lipase is a therapeutic target for Alzheimer's disease.

Pub. Date : 2012 Nov 29

PMID : 23122958






1 Functional Relationships(s)
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1 Although the molecular mechanisms underlying the beneficial effects produced by MAGL inhibition remain to be determined, our results suggest that MAGL, which regulates endocannabinoid and prostaglandin signaling, contributes to pathogenesis and neuropathology of AD, and thus is a promising therapeutic target for the prevention and treatment of AD. Endocannabinoids monoglyceride lipase Mus musculus