Title : Antidepressant-like effects of trazodone on a behavioral screen are mediated by trazodone, not the metabolite m-chlorophenylpiperazine.

Pub. Date : 1990 Feb 27

PMID : 2311675






1 Functional Relationships(s)
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1 m-Chlorophenylpiperazine (m-CPP) is a 5-HT1B and 5-HT1C agonist, weak 5-HT2 antagonist, and trazodone metabolite. 1-(3-chlorophenyl)piperazine 5-hydroxytryptamine receptor 1B Rattus norvegicus