Title : [Dexamethasone impairs immunosuppressive ability of mesenchymal stem cells].

Pub. Date : 2012 Oct

PMID : 23114146






2 Functional Relationships(s)
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1 After the Dex-treated MSC were co-cultured with IFN-gamma for 12 h, the immunoregulatory ability of MSC was recovered in a certain degree. Dexamethasone interferon gamma Homo sapiens
2 It is concluded that the Dex impairs the immunosuppressive ability of MSC, the IFN-gamma can protect and reverse the immunosuppressive ability of MSC impaired by Dex, so that, when the immunoregulatory activity of MSC is investigated, it is necessary to avoid adding Dex in the culture medium. Dexamethasone interferon gamma Homo sapiens