Title : Hydroxylation of (-)-epigallocatechin-3-O-gallate at 3'', but not 4'', is essential for the PI3-kinase/Akt-dependent phosphorylation of endothelial NO synthase in endothelial cells and relaxation of coronary artery rings.

Pub. Date : 2013 Feb

PMID : 23104077






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These findings suggest that the hydroxyl group at the 3"" position of the gallate ring is essential and, also, to some extent, the two hydroxyl groups at positions 3" and 4", for the EGCg-induced redox-sensitive activation of eNOS leading to the subsequent NO-mediated vascular relaxation. Gallic acid nitric oxide synthase 3 Homo sapiens