Title : Atorvastatin decreases Toll-like receptor 4 expression and downstream signaling in human monocytic leukemia cells.

Pub. Date : 2012 Sep

PMID : 23103560






1 Functional Relationships(s)
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1 RESULTS: Atorvastatin incubation resulted in significant decreases in the levels of TLR4 protein and mRNA, NF-kappaB expression, and levels of TNF-alpha, IL-6, and IL-1beta in LPS-induced THP-1 cells (P<0.01). Atorvastatin interleukin 6 Homo sapiens