Pub. Date : 2012
PMID : 23094196
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ketamine suppresses tumor necrosis factor (TNF) secretion by MRSA-stimulated RAW264.7 macrophages, and the mechanism likely involves N-methyl-D-aspartic acid (NMDA) receptor antagonism. | Ketamine | tumor necrosis factor | Mus musculus |
| 2 | NMDA inhibition suppressed TNF secretion by almost a third compared to the no-ketamine control. | Ketamine | tumor necrosis factor | Mus musculus |
| 3 | Ketamine-induced suppression of TNF secretion was intensified 10-15% when rapamycin was added, but not when LY294002 was added. | Ketamine | tumor necrosis factor | Mus musculus |