Title : Glucocorticoid receptor dimerization is required for proper recovery of LPS-induced inflammation, sickness behavior and metabolism in mice.

Pub. Date : 2013 Sep

PMID : 23089634






1 Functional Relationships(s)
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1 GR(dim)-LPS mice exhibited elevated and prolonged levels of plasma corticosterone (CORT), interleukin (IL)-6 and IL-10 (but not plasma tumor necrosis factor-alpha (TNFalpha)), enhanced early expression of brain TNFalpha, IL-1beta and IL-6 mRNA levels, and impaired later central TNFalpha mRNA expression. Corticosterone nuclear receptor subfamily 3, group C, member 1 Mus musculus