| Protein Name | nuclear receptor subfamily 3, group C, member 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14815 |
| Gene Symbol | Nr3c1 |
| UniProt | E9PUR6 (E9PUR6_MOUSE), E9PYV1 (E9PYV1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
376
Total Number of Articles : 764 |
Description |
nuclear receptor subfamily 3, group C, member 1 |
| Gene Summary |
Enables several functions, including identical protein binding activity; nuclear glucocorticoid receptor activity; and promoter-specific chromatin binding activity. Involved in several processes, including glial cell differentiation; nuclear receptor-mediated glucocorticoid signaling pathway; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including maternal behavior; regulation of primary metabolic process; and response to cortisol. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and leg muscle. Used to study primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anorexia nervosa; cocaine abuse; heroin dependence; and lung disease (multiple). Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |