Title : Zymosan induces NADPH oxidase activation in human neutrophils by inducing the phosphorylation of p47phox and the activation of Rac2: involvement of protein tyrosine kinases, PI3Kinase, PKC, ERK1/2 and p38MAPkinase.

Pub. Date : 2013 Jan 1

PMID : 23085266






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phosphorylation of the p47phox as well as Rac2 activation were inhibited by genistein a broad range protein tyrosine kinase inhibitor and by wortmannin a PI3Kinase inhibitor. Wortmannin Rac family small GTPase 2 Homo sapiens