Title : Protein disulfide isomerase modification and inhibition contribute to ER stress and apoptosis induced by oxidized low density lipoproteins.

Pub. Date : 2013 Mar 1

PMID : 23083489






1 Functional Relationships(s)
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1 These effects on PDI were mimicked by exogenous 4-HNE and prevented by the carbonyl-scavengers N-acetylcysteine and pyridoxamine, which reduced CHOP expression and toxicity by oxLDLs. Pyridoxamine prolyl 4-hydroxylase subunit beta Homo sapiens