Pub. Date : 2012 Nov 1
PMID : 23082722
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For this purpose, we generated hTERT-immortalized fibroblasts overexpressing the rate-limiting enzymes that promote ketone body production, namely BDH1 and HMGCS2. | Ketones | 3-hydroxy-3-methylglutaryl-CoA synthase 2 | Homo sapiens |
| 2 | In summary, ketone bodies behave as onco-metabolites, and we directly show that the enzymes HMGCS2, ACAT1/2 and OXCT1/2 are bona fide metabolic oncogenes. | Ketones | 3-hydroxy-3-methylglutaryl-CoA synthase 2 | Homo sapiens |