Pub. Date : 2012
PMID : 23075874
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previously, we reported that the uptake of dextran sodium sulfate (DSS) by macrophages activates the Nlrp3 inflammasome and that Nlrp3(-/-) mice are protected in the acute DSS colitis model. | dss | NLR family, pyrin domain containing 3 | Mus musculus |
| 2 | Previously, we reported that the uptake of dextran sodium sulfate (DSS) by macrophages activates the Nlrp3 inflammasome and that Nlrp3(-/-) mice are protected in the acute DSS colitis model. | dss | NLR family, pyrin domain containing 3 | Mus musculus |
| 3 | Of note, other groups have reported opposing effects in regards to DSS susceptibility in Nlrp3(-/-) mice. | dss | NLR family, pyrin domain containing 3 | Mus musculus |
| 4 | RESULTS: Nlrp3(-/-) mice treated with either DSS or TNBS exhibited attenuated colitis and lower mortality. | dss | NLR family, pyrin domain containing 3 | Mus musculus |