Title : Application of a substrate cocktail approach in the assessment of cytochrome P450 induction using cultured human hepatocytes.

Pub. Date : 2013 Feb

PMID : 23071008






2 Functional Relationships(s)
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1 Induction of the cytochrome P450 (CYP) family of enzymes by coadministered compounds can result in drug-drug interactions, as in the case of the coadministration of rifampicin with many CYP3A substrates, including midazolam. Midazolam cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Induction of the cytochrome P450 (CYP) family of enzymes by coadministered compounds can result in drug-drug interactions, as in the case of the coadministration of rifampicin with many CYP3A substrates, including midazolam. Midazolam cytochrome P450 family 4 subfamily F member 3 Homo sapiens