Title : Common polymorphisms in the complement system and susceptiblity to bacterial meningitis.

Pub. Date : 2013 Mar

PMID : 23068452






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rs1047286 is in strong linkage disequilibrium with Rs2230199 (C3 Arg102Gly), of which the Arg/Arg genotype was associated with higher CSF levels of C3 and lower levels of C5a and terminal complement complex (TCC; soluble C5b-9), indicating decreased consumption of C3 and less activation of the complement system. Arginine complement C5a receptor 1 Homo sapiens
2 Rs1047286 is in strong linkage disequilibrium with Rs2230199 (C3 Arg102Gly), of which the Arg/Arg genotype was associated with higher CSF levels of C3 and lower levels of C5a and terminal complement complex (TCC; soluble C5b-9), indicating decreased consumption of C3 and less activation of the complement system. Arginine complement C5a receptor 1 Homo sapiens