Title : Antagonists of toll like receptor 4 maybe a new strategy to counteract opioid-induced hyperalgesia and opioid tolerance.

Pub. Date : 2012 Dec

PMID : 23062774






1 Functional Relationships(s)
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1 We hypothesized that opioid antagonists such as naloxone and naltrexone, which were also demonstrated to be TLR4 antagonist, may have clinic application value in attenuation of opioid-induced hyperalgesia and tolerance. Naltrexone toll like receptor 4 Homo sapiens