PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23062774-6 2012 We hypothesized that opioid antagonists such as naloxone and naltrexone, which were also demonstrated to be TLR4 antagonist, may have clinic application value in attenuation of opioid-induced hyperalgesia and tolerance. Naltrexone 61-71 toll like receptor 4 Homo sapiens 108-112