Pub. Date : 2012 Dec
PMID : 23015612
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activated glucose-6-phosphate dehydrogenase is associated with insulin resistance by upregulating pentose and pentosidine in diet-induced obesity of rats. | Pentoses | glucose-6-phosphate dehydrogenase | Rattus norvegicus |
| 2 | Recent studies have shown that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via reduced nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. | Pentoses | glucose-6-phosphate dehydrogenase | Rattus norvegicus |
| 3 | Recent studies have shown that glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme for the pentose phosphate pathway, was involved in insulin resistance via reduced nicotinamide adenine dinucleotide phosphate, while the roles of pentose were not examined. | Pentoses | glucose-6-phosphate dehydrogenase | Rattus norvegicus |
| 4 | G6PD activities were increased in the pancreas and liver with upregulated pentose levels in serum, pancreas, and liver of OP rats. | Pentoses | glucose-6-phosphate dehydrogenase | Rattus norvegicus |
| 5 | Our results suggest that the upregulation of G6PD causes an increase in the accumulation of pentose and pentosidine, which might be associated with insulin resistance in the condition of obesity. | Pentoses | glucose-6-phosphate dehydrogenase | Rattus norvegicus |