Title : Bicarbonate-dependent, carbonate radical anion-driven tocopherol-mediated human LDL peroxidation: an in vitro and in vivo study.

Pub. Date : 2012 Nov

PMID : 23003200






3 Functional Relationships(s)
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1 CO(3)( -), generated in vitro by the SOD1/H(2)O(2)/bicarbonate system, readily promoted TMP, which was dependent on alpha-tocopherol and bicarbonate concentrations, and was inhibited by the CO(3)( -) scavenger ethanol; moreover, TMP induced in vitro by the SOD1/H(2)O(2)/bicarbonate system occurred in the presence of alpha-tocopherol that typically underwent slow oxidative consumption. Bicarbonates superoxide dismutase 1 Homo sapiens
2 CO(3)( -), generated in vitro by the SOD1/H(2)O(2)/bicarbonate system, readily promoted TMP, which was dependent on alpha-tocopherol and bicarbonate concentrations, and was inhibited by the CO(3)( -) scavenger ethanol; moreover, TMP induced in vitro by the SOD1/H(2)O(2)/bicarbonate system occurred in the presence of alpha-tocopherol that typically underwent slow oxidative consumption. Bicarbonates superoxide dismutase 1 Homo sapiens
3 CO(3)( -), generated in vitro by the SOD1/H(2)O(2)/bicarbonate system, readily promoted TMP, which was dependent on alpha-tocopherol and bicarbonate concentrations, and was inhibited by the CO(3)( -) scavenger ethanol; moreover, TMP induced in vitro by the SOD1/H(2)O(2)/bicarbonate system occurred in the presence of alpha-tocopherol that typically underwent slow oxidative consumption. Bicarbonates superoxide dismutase 1 Homo sapiens