Title : Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.

Pub. Date : 2012 Nov 2

PMID : 22992742






2 Functional Relationships(s)
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1 IQGAP1 knockdown also reduced the amount of GTP bound to GTPase-deficient RhoA/C mutants, suggesting that IQGAP enhances Rho activation by GEF(s) or stabilizes Rho-GTP. Guanosine Triphosphate Ras protein specific guanine nucleotide releasing factor 1 Homo sapiens
2 IQGAP1 knockdown also reduced the amount of GTP bound to GTPase-deficient RhoA/C mutants, suggesting that IQGAP enhances Rho activation by GEF(s) or stabilizes Rho-GTP. Guanosine Triphosphate Ras protein specific guanine nucleotide releasing factor 1 Homo sapiens